April’s networking event took place at Il Cortile in the heart of Little Italy. The restaurant’s employees and AstraZeneca representatives warmly welcomed NYCSHP members with open arms. Members caught up with one another while new acquaintances met, each with delicious red wine and sparkling water in hand.
President, Dr. Amisha Arya, opened the evening by greeting the attendees and thanking AstraZeneca. Vida Rosenfeld, Medical Science Liaison from AstraZeneca, introduced the evening’s speaker, Peter Toth, MD, PhD, and Professor at University of Illinois, College of Medicine. The presentation was titled “Advancing knowledge of hypertriglyceridemia.”
Dr. Toth’s presentation focused on raising awareness about hypertriglyceridemia and identifying causes. Dr. Toth discussed the epidemiology and pathophysiology of dyslipidemia. He explained the biochemical pathway of fatty acid biosynthesis and how lipid dysfunction occurs. The patients at higher risk of lipid abnormalities are those with insulin resistance and chronic kidney disease. These patients produce increased levels of LDL and increased levels of apo C-III lipoprotein. Such lipid abnormalities disrupt the body’s ability to metabolize fat from circulation leading to cardiovascular risks.
Primary causes of hypertriglyceridemia include familial history and lipoprotein lipase deficiency. Secondary causes include metabolic disease such as obesity, diabetes mellitus, insulin resistance, hypothyroidism, and nephrotic syndrome. Medications that can cause lipid dysfunction are estrogens, protease inhibitors, thiazide diuretics, beta-blockers, psychotropic agents such as Zyprexa, and steroids. Pregnant women in the second trimester who have hypertriglyceridemia are predisposed to pancreatitis and are at risk for premature cardiovascular disease. Triglyceride levels greater than 200mg/dl place patients at risk for acute pancreatitis. When measuring triglyceride levels, patients need to have fasted for at least 8 hours or else the reading is not informative. At the conclusion of the presentation, Dr. Toth welcomed questions from the audience. President-elect, Dr. Yi Guo, closed the presentation by announcing updates from NYCSHP.
Written by Jamie Chin
Photos by Jamie Chin